IDENTIFICATION AND VALIDATION OF BIOMARKERS FOR NON-ALCOHOLIC STEATOHEPATITIS (NASH) AND ACROSS THE SPECTRUM OF NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD)
Social Affairs & Human Rights
The central challenge to be addressed is to establish and validate non-invasive markers for classifying and evaluating subjects with NAFLD, and in particular to identify amongst those with NAFLD, individuals who have Nonalcoholic steatohepatitis (NASH). Identifying and validating these biomarkers will be crucial in furthering an understanding of the factors that drive the heterogeneity of NAFLD and in enabling accurate diagnosis of those with NASH. The ultimate challenge that will be addressed is to validate one or more NAFLD biomarkers that can serve as surrogates for development of clinically meaningful outcomes.
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